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K-Dense-AI / scientific-agent-skills

Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 250,000+ scientists worldwide. 177 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.

β–² 4.4k/7d β˜… 53k Python πŸ”₯ 1d ago
biopython / biopython

Official git repository for Biopython (originally converted from CVS)

β˜… 5.2k Python 1d ago
google / deepvariant

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

β˜… 3.8k Python 20d ago
materialsproject / pymatgen

Python Materials Genomics (pymatgen) is a robust materials analysis code that defines classes for structures and molecules with support for many electronic structure codes. It powers the Materials Project.

β˜… 2.0k Python today
scverse / scvi-tools

Deep probabilistic analysis of single-cell and spatial omics data

β˜… 1.7k Python today
thetahealth / mirobody

Turn scattered health data into answers you can trace. Self-hosted AI health data engine for lab reports, wearables and genetics, with a built-in MCP server. Run it with Docker and one LLM key, or keep every model local on llama.cpp.

β˜… 1.4k Python today
vgteam / vg

tools for working with genome variation graphs

β˜… 1.3k C++ today
scikit-bio / scikit-bio

scikit-bio: a community-driven Python library for bioinformatics, providing versatile data structures, algorithms and educational resources.

β˜… 1.3k Python 3d ago
scverse / gget

🧬 gget enables efficient querying of genomic reference databases

β˜… 1.2k Python 1d ago
ClawBio / ClawBio

πŸ¦– ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.

β˜… 1.2k Python today
hail-is / hail

Cloud-native genomic dataframes and batch computing

β˜… 1.1k Python today
pysam-developers / pysam

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

β˜… 911 Cython 5d ago
igvteam / igv

Integrative Genomics Viewer. Fast, efficient, scalable visualization tool for genomics data and annotations

β˜… 768 Java 4d ago
igvteam / igv.js

Embeddable genomic visualization component based on the Integrative Genomics Viewer

β˜… 736 JavaScript 4d ago
vcflib / vcflib

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

β˜… 687 C++ 18d ago
oschwengers / bakta

Rapid & standardized annotation of bacterial genomes, MAGs & plasmids

β˜… 686 Python 9d ago
biojava / biojava

:book::microscope::coffee: BioJava is an open-source project dedicated to providing a Java library for processing biological data.

β˜… 634 Java 21d ago
Ecogenomics / GTDBTk

GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.

β˜… 624 Python today
nf-core / sarek

Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing

β˜… 614 Nextflow today
oncologylab / fp-tools

Command-first ATAC-seq footprinting, motif analysis, and reproducible interactive reports

β˜… 584 Python 1d ago
ncbi / datasets

NCBI Datasets is a new resource that lets you easily gather data from across NCBI databases.

β˜… 562 Jupyter Notebook 7d ago
benjjneb / dada2

Accurate sample inference from amplicon data with single nucleotide resolution

β˜… 559 R πŸ”₯ 2mo ago
merenlab / anvio

An analysis and visualization platform for 'omics data

β˜… 544 Python today
dellytools / delly

DELLY2: Structural variant discovery by integrated paired-end and split-read analysis

β˜… 538 C++ 6d ago
styczynski / bioseqdb

Genomic sequence storage, indexing and alignment inside PostgreSQL: https://bioseqdb.com/

β˜… 240 VHDL 1d ago
dportik / Biotech-Job-Search-Engine

A configurable, open-source job-discovery system for biotech, genomics, computational biology, bioinformatics, and adjacent life-science roles.

β˜… 84 Python 2mo ago
wrab12 / awesome-spatial-transcriptomics

A curated list of tools, foundation models, datasets and tutorials for spatial transcriptomics and single-cell analysis, ordered the way an analysis goes.

β˜… 52 today
natera-open-source / vep-rs

A fast, memory-efficient variant effect predictor written in Rust: a from-scratch reimplementation of the Ensembl Variant Effect Predictor (VEP) that takes the same inputs and flags, emits VEP's consequence vocabulary in VEP's output formats, and annotates population-scale callsets two orders of magnitude faster than the Perl implementation.

β˜… 46 Rust today