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thetahealth / mirobody

Turn scattered health data into answers you can trace. Self-hosted AI health data engine for lab reports, wearables and genetics, with a built-in MCP server. Run it with Docker and one LLM key, or keep every model local on llama.cpp.

β–² ~14/7d β˜… 1.4k Python today
biopython / biopython

Official git repository for Biopython (originally converted from CVS)

β–² ~7/7d β˜… 5.2k Python today
google / deepvariant

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

β–² ~0/7d β˜… 3.8k Python 21d ago
soedinglab / MMseqs2

MMseqs2: ultra fast and sensitive search and clustering suite

β–² ~0/7d β˜… 2.2k C 2d ago
materialsproject / pymatgen

Python Materials Genomics (pymatgen) is a robust materials analysis code that defines classes for structures and molecules with support for many electronic structure codes. It powers the Materials Project.

β–² ~0/7d β˜… 2.0k Python 2d ago
scverse / scvi-tools

Deep probabilistic analysis of single-cell and spatial omics data

β–² ~0/7d β˜… 1.7k Python 1d ago
vgteam / vg

tools for working with genome variation graphs

β–² ~0/7d β˜… 1.3k C++ today
scikit-bio / scikit-bio

scikit-bio: a community-driven Python library for bioinformatics, providing versatile data structures, algorithms and educational resources.

β–² ~0/7d β˜… 1.3k Python 4d ago
scverse / gget

🧬 gget enables efficient querying of genomic reference databases

β–² ~0/7d β˜… 1.2k Python today
ClawBio / ClawBio

πŸ¦– ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.

β–² ~0/7d β˜… 1.2k Python 1d ago
hail-is / hail

Cloud-native genomic dataframes and batch computing

β–² ~0/7d β˜… 1.1k Python today
pysam-developers / pysam

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

β–² ~0/7d β˜… 911 Cython 7d ago
thackl / gggenomes

A grammar of graphics for comparative genomics

β–² ~0/7d β˜… 791 R 17d ago
igvteam / igv

Integrative Genomics Viewer. Fast, efficient, scalable visualization tool for genomics data and annotations

β–² ~0/7d β˜… 768 Java today
torognes / vsearch

Versatile open-source tool for microbiome analysis

β–² ~0/7d β˜… 761 C++ 11d ago
igvteam / igv.js

Embeddable genomic visualization component based on the Integrative Genomics Viewer

β–² ~0/7d β˜… 736 JavaScript 6d ago
vcflib / vcflib

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

β–² ~0/7d β˜… 687 C++ 20d ago
oschwengers / bakta

Rapid & standardized annotation of bacterial genomes, MAGs & plasmids

β–² ~0/7d β˜… 686 Python 10d ago
immunogenomics / harmony

Fast, sensitive and accurate integration of single-cell data with Harmony

β–² ~0/7d β˜… 676 R 6d ago
biojava / biojava

:book::microscope::coffee: BioJava is an open-source project dedicated to providing a Java library for processing biological data.

β–² ~0/7d β˜… 634 Java 23d ago
Ecogenomics / GTDBTk

GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.

β–² ~0/7d β˜… 624 Python 2d ago
nf-core / sarek

Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing

β–² ~0/7d β˜… 614 Nextflow today
scverse / squidpy

Spatial Single Cell Analysis in Python

β–² ~0/7d β˜… 611 Python 2d ago
oncologylab / fp-tools

Command-first ATAC-seq footprinting, motif analysis, and reproducible interactive reports

β–² ~0/7d β˜… 581 Python 2d ago
Ensembl / ensembl-vep

The Ensembl Variant Effect Predictor predicts the functional effects of genomic variants

β–² ~0/7d β˜… 578 Perl 1d ago
ncbi / datasets

NCBI Datasets is a new resource that lets you easily gather data from across NCBI databases.

β–² ~0/7d β˜… 563 Jupyter Notebook 8d ago
benjjneb / dada2

Accurate sample inference from amplicon data with single nucleotide resolution

β–² ~0/7d β˜… 559 R πŸ”₯ 2mo ago
sourmash-bio / sourmash

Quickly search, compare, and analyze genomic and metagenomic data sets.

β–² ~0/7d β˜… 557 Python 2d ago
merenlab / anvio

An analysis and visualization platform for 'omics data

β–² ~0/7d β˜… 544 Python today
dellytools / delly

DELLY2: Structural variant discovery by integrated paired-end and split-read analysis

β–² ~0/7d β˜… 538 C++ 7d ago
styczynski / bioseqdb

Genomic sequence storage, indexing and alignment inside PostgreSQL: https://bioseqdb.com/

β–² ~0/7d β˜… 238 VHDL 2d ago
dportik / Biotech-Job-Search-Engine

A configurable, open-source job-discovery system for biotech, genomics, computational biology, bioinformatics, and adjacent life-science roles.

β–² ~0/7d β˜… 85 Python 2mo ago
wrab12 / awesome-spatial-transcriptomics

A curated list of tools, foundation models, datasets and tutorials for spatial transcriptomics and single-cell analysis, ordered the way an analysis goes.

β–² ~0/7d β˜… 52 2d ago
natera-open-source / vep-rs

A fast, memory-efficient variant effect predictor written in Rust: a from-scratch reimplementation of the Ensembl Variant Effect Predictor (VEP) that takes the same inputs and flags, emits VEP's consequence vocabulary in VEP's output formats, and annotates population-scale callsets two orders of magnitude faster than the Perl implementation.

β–² ~0/7d β˜… 46 Rust today
jianshu93 / TurboANI

Homology-based ANI estimation at unprecedented scalesπŸ¦€