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google / deepvariant

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

β˜… 3.8k Python 20d ago
OpenGene / fastp

An ultra-fast all-in-one FASTQ preprocessor (QC/adapters/trimming/filtering/splitting/merging...)

β˜… 2.4k C++ 14d ago
samtools / samtools

Tools (written in C using htslib) for manipulating next-generation sequencing data

β˜… 2.0k C today
nf-core / rnaseq

RNA sequencing analysis pipeline using STAR, RSEM, HISAT2 or Salmon with gene/isoform counts and extensive quality control.

β˜… 1.4k Nextflow 3d ago
bacalhau-project / bacalhau

Community-driven, simple, yet powerful framework for fast, cost-effective distributed Compute over Data.

β˜… 874 Go 2d ago
s-andrews / FastQC

A quality control analysis tool for high throughput sequencing data

β˜… 624 Java 13d ago
etal / cnvkit

Copy number variant detection from targeted DNA sequencing

β˜… 617 Python 5d ago
nf-core / sarek

Analysis pipeline to detect germline or somatic variants (pre-processing, variant calling and annotation) from WGS / targeted sequencing

β˜… 614 Nextflow today
marcelm / cutadapt

Cutadapt removes adapter sequences from sequencing reads

β˜… 588 Python 1mo ago
styczynski / bioseqdb

Genomic sequence storage, indexing and alignment inside PostgreSQL: https://bioseqdb.com/

β˜… 240 VHDL 1d ago
Cliff-Lee / melodex

Open-source music player that turns your local library and connected sources into personalised listening journeys using Flow sequencing, taste memory, rediscovery, and optional LLM control.

β˜… 28 Python 3d ago
windmirrorai / nanomirrors

State-of-the-art bio cell models for inference and training. Minimal, readable, and produciton-ready.