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microsoft / qlib

Qlib is an AI-oriented Quant investment platform that aims to use AI tech to empower Quant Research, from exploring ideas to implementing productions. Qlib supports diverse ML modeling paradigms, including supervised learning, market dynamics modeling, and RL, and is now equipped with https://github.com/microsoft/RD-Agent to automate R&D process.

★ 50k Python 6d ago
deepmodeling / deepmd-kit

A deep learning package for many-body potential energy representation and molecular dynamics

★ 2.1k Python today
dynamicslab / pysindy

A package for the sparse identification of nonlinear dynamical systems from data

★ 1.9k Python 6d ago
pnnl / neuromancer

Pytorch-based framework for solving parametric constrained optimization problems, physics-informed system identification, and parametric model predictive control.

★ 1.4k Python 1d ago
mir-group / nequip

NequIP is a code for building E(3)-equivariant interatomic potentials

★ 970 Python 1d ago
gprMax / gprMax

gprMax is open source software that simulates electromagnetic wave propagation using the Finite-Difference Time-Domain Finite-Difference (FDTD) code for numerical modelling of Ground Penetrating Radar (GPR), antennas, radar and bioelectromagnetics

★ 893 Python 1d ago
leggedrobotics / pace-sim2real

PACE: A systematic approach for sim-to-real transfer of legged robots, identifying actuator and joint dynamics with standard joint encoders.

★ 808 Python 2d ago
mdtraj / mdtraj

An open library for the analysis of molecular dynamics trajectories

★ 738 Python 6d ago
jaheyns / CfdOF

Computational Fluid Dynamics (CFD) for FreeCAD based on OpenFOAM solver

★ 736 Python 13d ago
prody / ProDy

A Python Package for Protein Dynamics Analysis

★ 560 Python 16d ago
dynamicslab / hydrogym

An RL-Gym for Challenge Problems in Data-Driven Modeling and Control of Fluid Dynamics.

★ 555 Python today
aristoteleo / dynamo-release

Inclusive model of expression dynamics with conventional or metabolic labeling based scRNA-seq / multiomics, vector field reconstruction and differential geometry analyses

★ 510 Python 6d ago
pathsim / pathsim

A Python native dynamical system simulation framework in the block diagram paradigm.

★ 509 Python today
zju3dv / INTACT-JEPA

INTACT: Isomorphic Intent-to-Action Learning for Search-Free World Models.

★ 217 Python 10d ago
Ali-Marandi / PyFluidDynamics

A professional Python library for 2D incompressible Navier-Stokes simulations using the Finite Difference Method, with advanced visualization.

★ 108 Python 1mo ago
Pyruslili / Nocturne-Memory-Core

Nocturne Memory Core — A continuity layer for AI systems, connecting human-readable memory, selective Breath, Drive dynamics, latent notes, and evolving Trails. Evolved from Ombre Brain.让AI的记忆、状态与判断轨迹跨越会话继续抵达。一个连接记忆、主动记录与演化路径的连续性系统。樱花粉/灰烬黑双色前端

★ 105 Python 1mo ago
adobe-research / LDR

Official implementation of "Learning How the World Evolves: Extrapolative Video World Models via Latent Dynamics Reasoning"

★ 63 Python 1mo ago
ant-research / HTD-Refine

Code for "HTD-Refine: Natural Human Motion Recovery by Aligning High-Order Temporal Dynamics from Monocular Videos", CVPR2026

★ 60 Python 2mo ago
jack66g / spatial-memory-engine

A next-gen long-term memory engine for AI apps: self-organizing spatial regions, memory dynamics (Ebbinghaus reinforcement / decay / consolidation), and explainable 8-signal retrieval. Runs offline with zero config; works with any OpenAI-compatible LLM/embedding, cloud or local. Chinese-friendly. Benchmarked head-to-head vs Mem0 and bare RAG

★ 57 Python 11d ago
Yusuftmle / FlyBrain-HalfLife

Autonomous Drosophila melanogaster (MaleCNS v1.0 / FlyWire) connectome agent playing Half-Life via biophysical LIF neural dynamics, 60x60 retina transduction, and DirectInput.

★ 55 Python 23d ago
Xiuyiw / CFD-SCIPaper-Agent

Author-in-the-loop toolkit for turning mature CFD evidence into defensible research directions, reproducible figures, and traceable scientific prose.

★ 48 Python 1d ago
K-Dense-AI / drug-discovery-agent-skills

Agent Skills for small-molecule and protein therapeutics: cheminformatics, molecular ML, docking and dynamics, protein design platforms, and target-discovery knowledge graphs.

★ 45 Python 1d ago
OwenTWebb / slipstream

Desktop virtual wind tunnel: drop in an STL, get OpenFOAM CFD (drag/lift, pressure maps, flow slices, streamlines)

★ 44 Python 28d ago
cunhaozhu / AquaWAM

AquaWAM: A Dynamics-aware World Action Model for Underwater Embodied Agents

★ 35 Python 16d ago
DKrasauskas / shockFLOW

This is the official repo for the 1D/2D LBM transonic computational fluid dynamics solver, shockFLOW.