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K-Dense-AI / scientific-agent-skills

Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 250,000+ scientists worldwide. 177 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.

โ–ฒ 4.4k/7d โ˜… 53k Python ๐Ÿ”ฅ 1d ago
SakanaAI / AI-Scientist

The AI Scientist: Towards Fully Automated Open-Ended Scientific Discovery ๐Ÿง‘โ€๐Ÿ”ฌ

โ–ฒ 69/7d โ˜… 15k Jupyter Notebook ๐Ÿ”ฅ 10mo ago
xonsh / xonsh

๐Ÿš Python-powered shell. Full-featured, cross-platform and AI-friendly.

โ˜… 9.7k Python today
github / scientist

:microscope: A Ruby library for carefully refactoring critical paths.

โ˜… 7.8k Ruby ๐Ÿ”ฅ 4d ago
ruc-datalab / DeepAnalyze

DeepAnalyze is the first agentic LLM for autonomous data science. ๐ŸŽˆไฝ ็š„AIๆ•ฐๆฎๅˆ†ๆžๅธˆ๏ผŒ่‡ชๅŠจๅˆ†ๆžๅคง้‡ๆ•ฐๆฎ๏ผŒไธ€้”ฎ็”Ÿๆˆไธ“ไธšๅˆ†ๆžๆŠฅๅ‘Š๏ผ

โ˜… 4.7k Python 7d ago
foryourhealth111-pixel / Vibe-Skills

Intelligent Skill routing and workflow orchestration for AI agents โ€” +21.12 pp reward, โˆ’29.6% tokens on SkillsBench with DeepSeekV4Flash-VE.

โ˜… 3.7k Python today
OpenNSWM-Lab / FAROS

A blueprint-driven AutoResearch runtime for orchestrating AI research workflows from idea generation and experiments to paper writing and peer review.

โ˜… 3.0k Python 6d ago
openags / paper-search-mcp

MCP, CLI, Skills for searching and downloading academic papers from multiple sources like arXiv, PubMed, bioRxiv, etc.

โ˜… 2.9k Python 18d ago
apache / hamilton

Apache Hamilton helps data scientists and engineers define testable, modular, self-documenting dataflows, that encode lineage/tracing and metadata. Runs and scales everywhere python does.

โ˜… 2.6k Jupyter Notebook today
ai4s-research / open-science

Open Science Desktop โ€” local-first, model-agnostic AI research workbench for macOS, Windows & Linux. Open-source Claude Science desktop alternative built on Tauri + MCP + agent skills.

โ˜… 1.9k TypeScript today
tsinghua-fib-lab / AgentSociety

AgentSociety 2 is a modern, LLM-native agent simulation platform designed for social science research and experimental design. It provides a flexible framework for creating and managing intelligent agents in simulated environments.

โ˜… 1.4k Python 6d ago
NetLogo / NetLogo

turtles, patches, and links for kids, teachers, and scientists

โ˜… 1.2k Scala today
jkitchin / scimax

An emacs starterkit for scientists and engineers

โ˜… 1.1k Emacs Lisp today
xuzhougeng / wisp-science

Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.

โ˜… 1.0k Rust today
retentioneering / retentioneering-tools

Python toolkit, MCP server, and agent skills for reproducible, auditable clickstream and event log analytics. Helps AI agents, data scientists and analysts build, validate, and cross-check product analytics, quantitative UX, customer journeys, graph-based user flows, behavioral segmentation, A/B tests, process mining models, Markov chain simulation

โ˜… 935 Python 1d ago
kubeflow / kale

Kubeflowโ€™s superfood for Data Scientists

โ˜… 706 Python 2d ago
apache / bigtop

Bigtop is an Apache Foundation project for Infrastructure Engineers and Data Scientists looking for comprehensive packaging, testing, and configuration of the leading open source big data components.

โ˜… 682 Groovy 22d ago
jimmc414 / Kosmos

Kosmos: An AI Scientist for Autonomous Discovery - An implementation and adaptation to be driven by Claude Code or API - Based on the Kosmos AI Paper - https://arxiv.org/abs/2511.02824

โ˜… 596 Python 11d ago
damonwan1 / AutoScholarLoop

A multi-agent AUTO Research loop for idea discovery, experiment execution, evidence-grounded paper writing, quality audit, and live Web observation from AI group, CNIC, CAS.

โ˜… 575 Python 26d ago
GACWR / OpenUBA

A robust, and flexible open source User & Entity Behavior Analytics (UEBA) framework used for Security Analytics. Developed with luv by Data Scientists & Security Analysts from the Cyber Security Industry. [BETA]

โ˜… 522 Python 3d ago
yogsoth-ai / de-anthropocentric-research-engine

A 267-skill research graph in pure markdown โ€” 51 research operations built from 216 single-purpose steps, composed in any order with explicit backtracking. One npx install, no runtime, no MCP bindings. The AI is the researcher; you set the direction.

โ˜… 505 today
SakanaAI / AI-Scientist-v3

The Agentic Scientist: Orchestrating Coding Agents for Automated Scientific (Co-)Discovery

โ˜… 431 Python 2d ago
mikamikasuki / forest

FOREST is a research agent for long-horizon science, where evidence gets lost, errors compound, and goals drift. It explores ideas, reads literature, forms hypotheses, runs real experiments, analyzes results, revises paths, and builds a full paperโ€”all in an editable graph you can inspect, branch, redirect, with claims and figures linked to evidence

โ˜… 295 Python 3d ago
Tyche-MKR / scientific-agent-skills

Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 190,000+ scientists worldwide. 165 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.

โ˜… 81 Python 1mo ago
sagirimo / BioDSH

The bioinformatics agent desktop for clinicians and wet-lab scientists โ€” built on DeepSeek Harness. One-click installers, a skill store, offline mode.

โ˜… 61 Python 2d ago
sammargolis / DrugTargetWorld

DrugTargetWorld: a synthetic biobank for training and benchmarking AI scientists on end-to-end drug target discovery. Paper: arXiv:2610.09558

โ˜… 34 9d ago
EvoScientist / SearchJev

SearchJev: a fast and calibrated System-1 model for search agents (training code)

โ˜… 34 Python 16d ago
Scientist888-star / GDAFusion

[Pattern Recognition 2026] Generative Representation Learning with Information Disentanglement and Global Alignment for Infrared and Visible Image Fusion

โ˜… 30 Python 2mo ago